Synthox 25mcg Tablet 1 Strip

✔️ Uses of Synthox 25mcg Tablet

• Hypothyroidism

✔️ Administration: Synthox 25mcg Tablet

Synthox-25 should be taken on an empty stomach, ideally in the morning, with a full glass of water. Avoid consuming food, milk, or tea for at least 1 hour before and 2 hours after taking this medicine.

✔️ Consistency: Synthox 25mcg Tablet

Take the medication at the same time daily. It may take 6 to 8 weeks of consistent use to notice significant improvements in symptoms.

✔️ Lifelong Use: Synthox 25mcg Tablet

For most individuals, Synthox-25 is a lifelong medication. Do not discontinue use without consulting your doctor, as symptoms of hypothyroidism may return if stopped.

✔️ Missed Dose: Synthox 25mcg Tablet

If you miss a dose, take it as soon as you remember. However, if it is close to the next scheduled dose, skip the missed dose and resume your regular schedule. Do not double the dose.

✔️ Dietary Precautions:

Maintain a 4-hour gap between Synthox-25 and any antacids, calcium or iron supplements, or multivitamins, as these can reduce its effectiveness.

✔️ Mechanism of Action

Synthox-25 contains Levothyroxine Sodium, a synthetic form of thyroxine (T4), which replaces the deficient thyroid hormone in the body. T4 is converted to its more active form, triiodothyronine (T3), which regulates basal metabolic rate, energy utilization, and protein synthesis. This medication helps normalize metabolism, promote growth and development, and improve symptoms of hypothyroidism.

✔️ Side Effects of Synthox 25mcg Tablet

The most common side effects occur when the dose is higher than necessary, leading to symptoms of hyperthyroidism. These include:

• Palpitations or irregular heartbeat
• Anxiety, nervousness, and restlessness
• Diarrhea and vomiting
• Weight loss
• Flushing or feeling of warmth
• Insomnia or sleep disturbances

Severe Reactions:
In rare cases, high levels of thyroid hormone may cause serious complications like very high fever, irregular heartbeats, low blood pressure, confusion, or seizures. If you experience any of these, contact your doctor immediately.

✔️ Dosage Guidelines of Synthox 25mcg Tablet

Adults:

• Mild Hypothyroidism: Initial dose of 1.7 mcg/kg or 100-125 mcg daily, adjusted every 6-8 weeks as needed.
• Severe Hypothyroidism: Begin with 12.5-25 mcg daily, increasing by 25 mcg every 2-4 weeks.
• TSH Suppression: For thyroid cancer or nodules, higher doses (e.g., >2 mcg/kg/day) may be used to achieve target TSH levels.

Children:

Dosage is weight-dependent and adjusted for age:

• Newborns (1-3 months): 10-15 mcg/kg/day
• Infants (3-12 months): 6-10 mcg/kg/day
• Children (1-12 years): 4-6 mcg/kg/day
• Adolescents: 2-3 mcg/kg/day

✔️ Certain drugs can interfere with Synthox-25’s absorption or effectiveness. These include:

• Reduced Absorption: Antacids, calcium or iron supplements, bile acid sequestrants, sucralfate, and certain multivitamins.
• Altered Levels: Medications like phenytoin, carbamazepine, or rifampicin may reduce Synthox-25 levels.
• Increased Risk of Side Effects: Combining Synthox-25 with ketamine, sympathomimetics, or anticoagulants like warfarin may increase the risk of side effects such as hypertension or bleeding.

Inform your doctor about all medications and supplements you are taking to avoid adverse interactions.

✔️ Precautions and Warnings

• Patients with cardiovascular disease, long-standing hypothyroidism, or other chronic conditions should start on a lower dose to prevent complications like angina, arrhythmias, or high blood pressure.
• Monitor thyroid hormone levels regularly to ensure the correct dosage.
• Avoid using Synthox-25 for weight loss, as misuse can lead to serious health issues.
• Elderly patients and those with diabetes or epilepsy should take Synthox-25 under close supervision.

✔️ Storage Instructions

Store Synthox 25mcg in a cool, dry place below 30°C. Protect it from light and keep it out of the reach of children.

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